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Helmholtz Zentrum fur Infektionsforschung GmbH
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AllCells LLC
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Broad Institute Inc
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PreventionGenetics llc
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AllCells LLC
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Cureline Inc
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Etubics Inc
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AllCells LLC
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Shanghai TongRen pharmaceutical co ltd
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Image Search Results
Journal: PLoS Genetics
Article Title: Reduced monocyte and macrophage TNFSF15 /TL1A expression is associated with susceptibility to inflammatory bowel disease
doi: 10.1371/journal.pgen.1007458
Figure Lengend Snippet: ( A ) Peripheral blood monocytes from rs6478109 heterozygotes were differentiated into macrophages in the presence of M-CSF (n = 10) or ( B ) GM-CSF (n = 7) before examining allele-specific expression. ( C ) Macrophages derived in (A) were stimulated with LPS for 4 hours before examining allele-specific expression (n = 10, genomic DNA as for panel (A)). ASE was measured at rs4263839 (ratio of A/G reported) in the first intron of TNFSF15 . All individuals were heterozygous at both rs4263839 and rs6478109. rs4263839:A is in phase with the IBD-protective allele rs6478109:A in 1000 Genomes EUR subjects.
Article Snippet:
Techniques: Expressing, Derivative Assay
Journal: Heliyon
Article Title: SHANK2-AS3: A potential biomarker for Parkinson's disease and its role in neuronal apoptosis via NF-κB signaling in SH-SY5Y cells
doi: 10.1016/j.heliyon.2024.e38822
Figure Lengend Snippet: Reanalysis of Differentially Expressed lncRNAs in PD Patients and Healthy Controls. (A) Volcano plot illustrating differentially expressed genes in PD patients compared to healthy controls. (B) KEGG enrichment analysis of dysregulated of lncRNAs in PD patients relative to controls. (C) Relative expression levels of SHANK2-AS3 in peripheral blood of PD patients versus elderly healthy controls. (D) Validated the expression of SHANK2-AS3 in the PD patients compared with healthy controls. (E) ROC curves demonstrating the diagnostic utility of SHANK2-AS3 levels in distinguishing PD patients from elderly individuals. Data represented as mean ± SD; ∗∗ p < 0.01.
Article Snippet: The
Techniques: Expressing, Diagnostic Assay